Radiosensitivity of Human T-lymphocytes Proliferating in Long Term Culture

Abstract
A method is described for determining the radiation sensitivity of dividing human T-lymphocytes in long-term culture. The results are fitted to a single-hit multi-target model. For 60Co .gamma. radiation Do [mean lethal dose] values of cells from 5 normal individuals range from 0.99-1.37 Gy [gray] with an overall Do of 1.09 Gy, and the extrapolation numbers range from 1.20 to 1.71 with an overall extrapolation number of 1.42.