Some Properties of a Bacterial-Inhibitory Substance Produced by a Mold

Abstract

Filtrates of a mold closely related to Penicillium notatum could inhibit the growth of certain bacteria. The inhibitory substance is not identical with, but closely related to, the pigment which develops simultaneously. It is relatively thermostable. It is volatile under certain conditions. It contains enzymes, notably amylase and catalase. The pH increases in parallel with it, but when once formed, alterations in pH do not affect it. It does not cause a change in the charge on the bacterial oxidation-reduction potential.