THE PATHOLOGIC EFFECTS OF INTRAVENOUSLY ADMINISTERED SOLUBLE ANTIGEN-ANTIBODY COMPLEXES
Open Access
- 1 February 1960
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 111 (2), 195-200
- https://doi.org/10.1084/jem.111.2.195
Abstract
The intravenous administration to rats of soluble antigen-antibody complexes in antigen excess resulted in acute glomerulonephritis. This occurred with both rabbit antiovalbumin and rabbit anti-bovine serum albumin systems. The rats so treated regularly showed proteinuria and elevation of blood urea nitrogen. These findings are compared with those reported in rats injected with anti-kidney serum.This publication has 3 references indexed in Scilit:
- THE PATHOLOGIC EFFECTS OF INTRAVENOUSLY ADMINISTERED SOLUBLE ANTIGEN-ANTIBODY COMPLEXESThe Journal of Experimental Medicine, 1960
- Localization of colloidal substances in vascular endothelium, a mechanism of tissue damage. II. Experimental serum sickness with acute glomerulonephritis induced passively in mice by antigen-antibody complexes in antigen excess.1959
- IMMEDIATE OR DELAYED NEPHRITIS IN RATS PRODUCED BY DUCK ANTI-RAT-KIDNEY SERA1957