THE PATHOLOGIC EFFECTS OF INTRAVENOUSLY ADMINISTERED SOLUBLE ANTIGEN-ANTIBODY COMPLEXES
Open Access
- 1 February 1960
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 111 (2), 181-194
- https://doi.org/10.1084/jem.111.2.181
Abstract
The intravenous administration to mice of soluble antigen-antibody complexes in antigen excess resulted in a high incidence of glomerulonephritis and less frequently in endocarditis or arteritis. These lesions are present within 48 hours of the first of 3 injections and disappear within 2 weeks.Keywords
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