Isolation of the opioid heptapeptide Met-enkephalin [Arg6,Phe7] from bovine adrenal medullary granules and striatum.
Open Access
- 1 December 1979
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 76 (12), 6680-6683
- https://doi.org/10.1073/pnas.76.12.6680
Abstract
Bovine adrenal chromaffin granules contain, in addition to Met-enkephalin and Leu-enkephalin, at least 3 small peptides with opiate receptor activity. One of the these adrenal peptides was purified to homogeneity and its sequence was shown to be Met-enkephalin-[Arg6,Phe7]. This heptapeptide was also found in beef striatal extracts in amounts comparable to those of Leu-enkephalin.Keywords
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