Antigens Common to Scabies and House Dust Mites

Abstract

Antigens (25) were demonstrated in a crude Dermatophagoides farinae (DF) extract by means of crossed immunoelectrophoresis (CIE), using a rabbit anti-DF serum. With the same antiserum, 4 antigens were demonstrated in a scabies mite preparation, indicating an immunological relationship between these scabies antigens and some of the DF antigens. In tandem CIE experiments the DF antigens were partly identical to 3 of the scabies antigens. No IgE antivity against any of these scabies antigens was evident in pooled sara from patients with house dust mite allergy by crossed radioimmunoelectrophoresis. One such patient had IgE antibodies to a DF antigen and a partial identical scabies antigen.