A STUDY OF THE SURVIVAL AND FUNCTION OF HOMOGRAFTED THYROID TISSUE IN MEMBRANE FILTER CHAMBERS IN THE RAT1
- 1 March 1960
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 66 (3), 392-402
- https://doi.org/10.1210/endo-66-3-392
Abstract
Thyroid tissue has been successfully homografted in Millipore diffusion chambers between rats that have been shown routinely to reject skin homografts. In such grafted animals, histological sections of chambers removed have revealed normal thyroid tissue and colloid-filled acini in 70% at 1 month and 44% at 4 months. Further corroborative evidence of functional viability has been based on a significant uptake of a tracer dose of iodine131 given prior to removal of the chambers, and on radio-autographs obtained. Problems relating to membrane thickness and to chamber breakage are discussed and the question of possible tissue adaptation to the host with the passage of time is raised.Keywords
This publication has 6 references indexed in Scilit:
- The functional activity of thyroid isografts within diffusion chambers in miceExperimental Cell Research, 1959
- LONG-TERM SURVIVAL OF INTRASTRAIN HOMOGRAFTS IN COMMERCIALLY BRED RATSPlastic and Reconstructive Surgery, 1959
- Growth of Mouse Ascites Tumor Cells in Diffusion Chambers. I. Studies of Growth Rate of Cells and of the Rate of Entry of Antibody2JNCI Journal of the National Cancer Institute, 1958
- Functional Survival of Ovarian Homografts within Millipore Filter Chambers in the Castrate Rat.Experimental Biology and Medicine, 1957
- Trans-filter induction of tubules in mouse metanephrogenic mesenchymeExperimental Cell Research, 1956
- The Diffusion-Chamber Technique Applied to a Study of the Nature of Homograft ResistanceJNCI Journal of the National Cancer Institute, 1954