Quantitative analysis of coronary arteriograms by microprocessor cinevideodensitometry
- 1 September 1987
- journal article
- research article
- Published by Wiley in Catheterization and Cardiovascular Diagnosis
- Vol. 13 (5), 291-300
- https://doi.org/10.1002/ccd.1810130502
Abstract
A rapid microprocessor technique for mesuring the cross‐sectional area, diameter, and relative percentage stenosis of coronary atherosclerotic lesions by cinevideodensitometric analysis was developed and validated. Video images of projected 35‐mm coronary arteriographic cine frames were analyzed from cinevideodensitometric profile curves recorded for the catheter shaft, normal artery, and stenotic segment. In radiographic phantom studies of calibrated, contrast‐filled, plexiglass cylinders, cinevideodensitometric measurements correlated linearly with percentage relative stenosis (r = 0.98; SEE = 4.1%), diameter (r = 0.99; SEE = 0.12 mm), and cross‐sectional area (r = 0.99; SEE = 0.32 mm2). In postmortem studies of two patients dying after coronary arteriography, cross‐sectional areas of arterial segments measured by cinevideodensitometry correlated well (r = 0.99; SEE = 0.71 mm) with areas of acrylic resin casts of the coronary arteries. Intraobserver variability (r = 0.99; SEE = 2.6%) and interobserver variability (r = 0.96; SEE = 5.3%) of cinevideodensitometric measurements of coronary arteriograms were low. Additionally, percentage relative stenosis measured in the right anterior oblique projection correlated well with measurements in the left anterior oblique projection (r = 0.98; SEE = 0.11 mm2) of patients with eccentric stenotic lesions. Lastly, cinevideodensitometric measurements were significantly (p < 0.05) more reproducible than caliper measurements. This inexpensive dedicated microprocessor system provides rapid cinevideodensitometric measurements of coronary arterial dimensions, without requiring manual tracing of arterial segments or the major expense of a mainframe computer system.Keywords
This publication has 25 references indexed in Scilit:
- The value of lesion cross-sectional area determined by quantitative coronary angiography in assessing the physiologic significance of proximal left anterior descending coronary arterial stenoses.Circulation, 1984
- Does Visual Interpretation of the Coronary Arteriogram Predict the Physiologic Importance of a Coronary Stenosis?New England Journal of Medicine, 1984
- Quantification of relative coronary arterial stenosis by cinevideodensitometric analysis of coronary arteriograms.Circulation, 1984
- Computerized image analysis for quantitative measurement of vessel diameter from cineangiograms.Circulation, 1983
- Quantitative coronary angiography: measurement of the "critical" stenosis in patients with unstable angina and single-vessel disease without collaterals.Circulation, 1979
- Quantitative coronary arteriography: estimation of dimensions, hemodynamic resistance, and atheroma mass of coronary artery lesions using the arteriogram and digital computation.Circulation, 1977
- Variability in the analysis of coronary arteriograms.Circulation, 1977
- Observer agreement in evaluating coronary angiograms.Circulation, 1975
- Discrepancies Between Cineangiographic and Postmortem Findings in Patients with Coronary Artery Disease and Recent Myocardial RevascularizationCirculation, 1974
- Correlation of the Antemortem Coronary Arteriogram and the Postmortem SpecimenCirculation, 1973