Hydroxamic Acid-Based Bisubstrate Analog Inhibitors of Ras Farnesyl Protein Transferase
- 1 January 1996
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 39 (21), 4197-4210
- https://doi.org/10.1021/jm960190h
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Peptide based P21RAS farnesyl transferase inhibitors: systematic modification of the tetrapeptide CA1A2X motifBioorganic & Medicinal Chemistry Letters, 1994
- Rational design of potent carboxylic acid based bisubstrate inhibitors of ras farnesyl protein transferaseBioorganic & Medicinal Chemistry Letters, 1994
- Phenol based tripeptide inhibitors of ras farnesyl protein transferaseBioorganic & Medicinal Chemistry Letters, 1994
- Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeuticCell, 1994
- Structure-activity studies on the retinal rod outer segment isoprenylated protein methyltransferaseJournal of the American Chemical Society, 1992
- Preferential inhibition of the oncogenic form of RasH by mutations in the GAP binding/“effector” domainCell, 1991
- Lining up the evidenceNature, 1989
- ras GENESAnnual Review of Biochemistry, 1987
- Chirality transfer in stereoselective synthesis. A highly stereoselective synthesis of optically active vitamin E side chainsThe Journal of Organic Chemistry, 1983
- N-Methylation of O-benzyl-.alpha.-N-(alkoxycarbonyl)-.alpha.-amino acid hydroxamate derivativesThe Journal of Organic Chemistry, 1981