Abstract
The effects of psychological intervention on multilevel stress responding in 25 patients newly diagnosed as having breast cancer were studied. Specifically, biofeedback and cognitive therapies were employed as treatments with 24-hr. urinary cortisol and state anxiety as dependent variables. The proportion of treated patients showing improvement exceeded that of non-treated patients on both variables. Most significantly, Cortisol levels among the 12 treated patients were reduced relative to those of control patients. These results are discussed for their relevance to psychoimmunology.