STUDIES ON SYMPATHOMIMETIC ACTION OF ACETALDEHYDE

Abstract

Acetaldehyde Injected into the perfuslon circuit markedly intensified the secretion of both epinephrine and norepinephrine from the adrenal medulla. When tyramine was introduced into the perfusion fluid, output of catecholamine remained at the control level. A significant increase in output of catecholamlnes by injection of acetaldehyde was also observed in the preparations perfused with Ca-free Locke''s solution and this action of acetaldehyde was blocked by neither hexamethonium or atropine.