MUCOLYTIC ENZYME SYSTEMS. VIII. INHIBITION OF HYALURONIDASE BY HUMAN BLOOD SERUM DURING THE NORMAL MENSTRUAL CYCLE AND PREGNANCY 1

Abstract

Studies were carried out on the inhibitory effect of blood sera from 10 normal women during various phases of the menstrual cycle, and from 16 women with uncomplicated pregnancies before, during and after delivery. The highest inhibitor levels tended to occur during menstruation, although the individual variation in this elevation was great. The data do not permit of a correlation with sex hormonal changes. No significant change was found during pregnancy or labor. A marked post-partum rise was observed which reached its maximum from the 2d to 5th days after delivery.