Pharmaceutical counterfeiting
- 14 December 2004
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in The Analyst
- Vol. 130 (3), 271-279
- https://doi.org/10.1039/b407759h
Abstract
Pharmaceutical counterfeiting is becoming a serious problem both in developed and developing countries. This paper considers the extent of the problem and provides several examples of drugs which have been counterfeited. Additionally, the effects of counterfeit products on consumers, health care providers, drug manufacturers and governments are discussed. Several of the currently used methods of detection are described and these include near-infrared spectroscopy, Raman spectroscopy, isotopic characterization, tensiography, chromatographic and mass spectrometric approaches. Finally, anti-counterfeiting measures such as the use of holograms, tracers and taggants and electronic tracking are summarized.Keywords
This publication has 20 references indexed in Scilit:
- Analysis of betamethasone, dexamethasone and related compounds by liquid chromatography/electrospray mass spectrometryRapid Communications in Mass Spectrometry, 2004
- Classification of ecstasy tablets using trace metal analysis with the application of chemometric procedures and artificial neural network algorithmsThe Analyst, 2004
- Identification of the ?wrong? active pharmaceutical ingredient in a counterfeit Halfan? drug product using accurate mass electrospray ionisation mass spectrometry, accurate mass tandem mass spectrometry and liquid chromatography/mass spectrometryRapid Communications in Mass Spectrometry, 2003
- Determination of the Information Depth and Sample Size for the Analysis of Pharmaceutical Materials Using Reflectance Near-Infrared MicroscopyApplied Spectroscopy, 2002
- Strategies for Constructing the Calibration Set in the Determination of Active Principles in Pharmaceuticals by Near Infrared Diffuse Reflectance SpectrometryThe Analyst, 1997
- Interpretive Spectroscopy for Near InfraredApplied Spectroscopy Reviews, 1996
- Quality control in manufacturing process by near infrared spectroscopyJournal of Pharmaceutical and Biomedical Analysis, 1995
- Chemical profiling of pharmaceuticals by capillary electrophoresis in the determination of drug originJournal of Chromatography A, 1994
- The use of Fourier Transform Raman spectroscopy in the forensic identification of illicit drugs and explosivesSpectrochimica Acta Part A: Molecular Spectroscopy, 1990
- Simple techniques to detect and identify phentermine adulterationForensic Science International, 1983