Effect of Hypophysectomy on Several Rat Adrenal NADPHGenerating and Oxidizing Systems
- 1 October 1964
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 75 (4), 506-513
- https://doi.org/10.1210/endo-75-4-506
Abstract
The effect of hypophysectomy on glucose-6-phosphate dehydrogenase, 6- phosphogluconate dehydrogenase, isocitrate dehydrogenase, NADPH-cytochrome c reductase, glutathione reductase and pyridine nucleotide transhydrogenase in rat adrenal has been studied. A fall in activity of glucose- 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and glutathione reductase was observed following hypophysectomy. This fall appears to be insignificant at the time when corticosteroid secretion decreases. A study of the subcellular distribution of the particulate enzymes was also performed. (Endocrinology75: 506, 1964)Keywords
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