Axonal microtubules necessary for generation of sodium current in squid giant axons: II. Effect of colchicine upon asymmetrical displacement current
- 1 September 1983
- journal article
- research article
- Published by Springer Nature in The Journal of Membrane Biology
- Vol. 77 (2), 93-99
- https://doi.org/10.1007/bf01925859
Abstract
Effect of internal colchicine on asymmetrical displacement currents was studied by internally perfusing squid giant axons with a solution containing colchicine. It was found that (1) asymmetrical displacement currents were composed of two parts; colchicine-sensitive and colchicine-resistant; that (2) the colchicine-sensitive part had a definite rising phase while the colchicine-resistant one showed an instantaneous jump, followed by exponential decay; and that (3) the colchicine-sensitive part related to normal Na channels.This publication has 21 references indexed in Scilit:
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