Uracil-uric Refractory Anemia with Peroxidase Negative Neutrophils

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Abstract
A peculiar disorder of a 7 year-4 month -old girl is described which is characterized by a refractory hypochromic anemia with megaloblastic bone marrow of a slight degree, an occurrence of the neutrophils which are negative to all the stains for peroxidase, oxidase, Sudan-black- B and succinic dehydrogenase, a urinary output of uracil uridine monophosphate (UMP) and urdine diphosphate (UDP), and fatal outcome due to sepsis with leukemoid blood picture. A term "Uracil-uric Refractory Anemia with Peroxidase Negative Neutrophils" is suggested for this new disorder.
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