Acute Circulatory Collapse of the Adrenalectomized Dog Following Plasma Infusion
- 1 May 1958
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 6 (3), 294-300
- https://doi.org/10.1161/01.res.6.3.294
Abstract
Adrenalectomized dogs maintained on desoxyeorticosterone acetate developed a fatal circulatory collapse when given normal dog plasma. They showed general restlessness, a rapid fall in blood pressure and cardiac index, a decline in central venous pressure and general prostration. Most dogs developed a bloody diarrhea and a minority showed edematous swelling of the face with itching. Animals with intact spleens exhibited marked hemoconcentration, splenectomized animals did not. Blood and plasma specific gravity determinations offered no evidence for gross plasma loss. Diphenhydramine prevented the collapse.Keywords
This publication has 7 references indexed in Scilit:
- Epinephrine and Resistance of Hypophysectomized and Adrenalectomized Rats to Stressor AgentsAmerican Journal of Physiology-Legacy Content, 1954
- Protection Afforded by Aqueous-Alcohol Solutions of Cortisone Against Dextran.Experimental Biology and Medicine, 1953
- Cortisone Fore-Treatment of Adrenalectomized Rats Infused With Globin and DextranAmerican Journal of Physiology-Legacy Content, 1953
- Circulatory Factors in Adrenal Crisis in the DogAmerican Journal of Physiology-Legacy Content, 1951
- *TOXICITE AIGUE COMPAREE DE QUELQUES ANTIHISTAMINIQUES DE SYNTHESE CHEZ LE RAT1950
- THE EFFECT OF DESOXYCORTICOSTERONE ACETATE AND OF BLOOD SERUM TRANSFUSIONS UPON THE CIRCULATION OF THE ADRENALECTOMIZED DOGAmerican Journal of Physiology-Legacy Content, 1941
- The Function of the Adrenal Cortical Hormone and the Cause of Death from Adrenal InsufficiencyScience, 1933