Effect of Dialyzed Enterogastrone Upon Twelve-Hour Nocturnal Gastric Secretion in Man.

Abstract
The HC1 output in the 12-hr. nocturnal gastric secretion of 4 peptic ulcer patients was unchanged following the intramusc. admn. of 200-2000 mg. of a dialyzed prepn. of enterogastrone. Gastric secretion was reduced slightly in 1 and markedly in 5 of 6 patients with peptic ulcer given 5000 mg. The transitory inhibition consisted chiefly of a decrease in the concn. of acid and, to a lesser extent, of the vol. of secretion.