BLOOD REGENERATION IN SEVERE ANEMIA

Abstract

It seems clear that the anemic dog can conserve foreign hemoglobin given intravenously and reconstruct from this material new dog hemoglobin. It appears obvious that the goose and sheep hemoglobin must be katabolized before this material can be utilized. All hemoglobin including dog hemoglobin given intravenously may be broken down before it is utilized in the body. A little more time is required for the utilization of sheep and goose hemoglobin as compared with dog hemoglobin. This may indicate that a portion of injected dog hemoglobin may be utilized direct by the marrow cells without the usual cycle of disintegration and synthesis. These experiments illustrate beautifully the careful conservation by the body of materials suit-able for hemoglobin construction, given the stress and depletion of a long continued anemia due to loss of blood.