REDUCTIVE DEGRADATION OF PYRIMIDINES II. Clostridium uracilicum
- 1 February 1957
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 73 (2), 225-229
- https://doi.org/10.1128/jb.73.2.225-229.1957
Abstract
Evidence is presented for the reductive pathway of uracil degradation by cell extracts of Clostridium uracilicum. Dihydrouracil and B-ureido-propionic acid were isolated and identified as intermediates in the conversion of uracil to [beta]-alanine, carbon dioxide and ammonia. Di-phosphopyridine nucleotide is required for the reduction of uracil to dihydrouracil and cannot be replaced by triphosphopyridine nucleotide. The significance of the reductive pathway of pyrimidine metabolism is discussed.Keywords
This publication has 22 references indexed in Scilit:
- REDUCTIVE DEGRADATION OF PYRIMIDINES I. , Clostridium uracilicum Nov. specJournal of Bacteriology, 1957
- Chromatography of Pyrimidine Reduction ProductsAnalytical Chemistry, 1956
- Enzymic interconversion of hydrouracil and β-ureidopropionic acidBiochimica et Biophysica Acta, 1955
- CARBAMYL PHOSPHATE, THE CARBAMYL DONOR IN ENZYMATIC CITRULLINE SYNTHESIS1Journal of the American Chemical Society, 1955
- ENZYMATIC SYNTHESIS AND BREAKDOWN OF A PYRIMIDINE, OROTIC ACIDPublished by Elsevier ,1955
- ENZYMATIC SYNTHESIS AND BREAKDOWN OF A PYRIMIDINE, OROTIC ACIDPublished by Elsevier ,1954
- Enzymic synthesis and breakdown of a pyrimidine, orotic acidBiochimica et Biophysica Acta, 1953
- ON THE DECOMPOSITION OF PYRIMIDINES BY BACTERIA IJournal of Bacteriology, 1952
- ON THE DECOMPOSITION OF PYRIMIDINES BY BACTERIA IIJournal of Bacteriology, 1952
- DETERMINATION OF CITRULLINE AND ALLANTOIN AND DEMONSTRATION OF CITRULLINE IN BLOOD PLASMAPublished by Elsevier ,1944