Suramin: a reversible P2‐purinoceptor antagonist in the mouse vas deferens
Open Access
- 1 February 1988
- journal article
- research article
- Published by Wiley in British Journal of Pharmacology
- Vol. 93 (2), 243-245
- https://doi.org/10.1111/j.1476-5381.1988.tb11427.x
Abstract
The trypanocide Suramin was tested as a possible antagonist at the P2-purinoceptor of the mouse vas deferens. At a concentration of 100 μm, Suramin antagonized the response to α,β-methylene ATP, while responses to carbachol and noradrenaline were unaffected. These results suggest that Suramin may provide a starting point for the development of specific antagonists for P2-purinoceptors.This publication has 11 references indexed in Scilit:
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