THE EFFECT OF EXTRACT OF THE POSTERIOR HYPOPHYSIS ON THE LOSS OF WATER BY FROGS IN A DRY ENVIRONMENT

Abstract

The loss of normal body water by frogs (Rana pipiens) in a dry environment is inhibited for a period of 3 hrs. by injs. of pituitrin, pitressin and pitocin providing that the frogs are kept out of a draft and heat and this loss of water is not greater in the dark than in the light. The smallest dose of pituitrin causing this reaction to a maximal degree and the length of time over which pituitrin is effective are the same as in the reaction causing an uptake of water by frogs in water and injected with pituitrin.