Bioactive Compounds from Aquatic and Terrestrial Sources
- 1 July 1990
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 53 (4), 771-792
- https://doi.org/10.1021/np50070a001
Abstract
The world of nature provides a never-ending set of fascinating problems for the chemist. Many of the most intriguing problems, however, concern compounds available in only truly minute quantities. One solution is to focus on bioassay-guided separations. In so doing one can isolate compounds with novel structures or unsuspected activities from almost any phylum, including tunicates, sponges, insects, or even the much-studied terrestrial plants, as exemplified in several recent studies in our laboratory involving activities ranging from antiviral and antimicrobial activity to cytotoxicity and immunomodulation. Moreover, newer spectroscopic techniques, especially fast atom bombardment mass spectrometry and tandem mass spectrometry, enhance one''s ability to study compounds present in minute quantities, including those of importance to the host organism, such as neuropeptides in insects or marine invertebrates.This publication has 27 references indexed in Scilit:
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