Occurrence of Eicosadienoic Acids in Liver Lipids of Rats Fed Partially Hydrogenated Soybean Fat

Abstract

Male rats were fed for 5 months diets containing 10% or 20% partially hydrogenated soybean fat. The liver lipids were extracted, fractionated and the fatty acid composition of the fractions determined. Among the fatty acids in the phospholipid fraction from rats fed the 20% partially hydrogenated fat were substantial amounts of eicosadienoic acids. The structures: 5,11-20:2, 6,11-20:2, 5,13-20:2, 8,13-20:2 and 8,11-20:2 have been suggested. Their appearance was accompanied by a decrease in the concentration of eicosatrienoic and eicosatetraenoic acids, indicating a hindrance in the interconversion of unsaturated fatty acids, in particular at the acyl desaturation step.