Abnormal metabolism of secondary bile acids in patients with cirrhosis
Open Access
- 1 May 1970
- Vol. 11 (5), 420-422
- https://doi.org/10.1136/gut.11.5.420
Abstract
The composition of bile acids in human bile was determined in bile-rich duodenal fluid on four consecutive days in a group of seven patients with cirrhosis and eight control patients with no liver disease. There was a marked reduction of secondary biliary bile acids in cirrhotic patients. Possible mechanisms for these changes are discussed.Keywords
This publication has 8 references indexed in Scilit:
- Degradation of bile salts by human intestinal bacteria.Gut, 1968
- The effect of oral neomycin on the conversion of cholic acid to deoxycholic in manArchives of Biochemistry and Biophysics, 1963
- The Formation and Metabolism of Bile Acids under Different ConditionsPublished by Elsevier ,1959
- On the conjugation and formation of bile acids in the human liver. I. On the excretion of bile acids by patients with postoperative choledochostomy drainage; bile acids and steroids 61.1958
- A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUESJournal of Biological Chemistry, 1957
- Turnover and Nature of Fecal Bile Acids in Germfree and Infected Rats Fed Cholic Acid-24-14C. Bile Acids and Steroids 41.Experimental Biology and Medicine, 1957
- On the Formation of Deoxycholic Acid from Cholic Acid in the Rabbit. Bile Acids and Steroids 48.Acta Chemica Scandinavica, 1957
- Metabolism of Desoxycholic Acid in the Rabbit: Bile, acids and Steroids 28Acta Physiologica Scandinavica, 1955