HORMONALLY INDUCED MAMMARY GROWTH AND LACTATION IN THE ABSENCE OF THE THYROID
- 1 August 1955
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 57 (2), 153-157
- https://doi.org/10.1210/endo-57-2-153
Abstract
Hypophysectomized-adrenalectomized-gonadectomized rats whose thyroids had been ablated by surgery and/or I131 showed lobulo-alveolar mammary growth following injections of estrone, progesterone, lactogenic hormone and growth hormone for 1 week. When further injections of lactogenic hormone and growth hormone, plus hydrocortisone acetate, were given for an additional 1 week, the glands secreted an abundance of milk. O2 consumption of the rats considered to be athyroidal was about one half of the normal rate, or one half of the rate seen in such athyroidal animals injected with thyroxin.Keywords
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