NMR and molecular modeling study of the conformations of taxol and of its side chain methylester in aqueous and non-aqueous solution.
- 1 July 1993
- journal article
- Published by Elsevier in Tetrahedron
- Vol. 49 (30), 6545-6560
- https://doi.org/10.1016/s0040-4020(01)81823-8
Abstract
No abstract availableThis publication has 26 references indexed in Scilit:
- Taxol: Quantitative Internuclear Proton-Proton Distances in CDCl3 Solution from nOe Data: 2D NMR Roesy Buildup Rates at 500 MHzJournal of Natural Products, 1992
- A practical, highly enantioselective synthesis of the taxol side chain via asymmetric catalysis.The Journal of Organic Chemistry, 1992
- Nuclear Overhauser Effect Spectroscopy (NOESY) and Dihedral Angle Measurements in the Determination of the Conformation of Taxol in SolutionSpectroscopy Letters, 1992
- Phase II Trial of Taxol, an Active Drug in the Treatment of Metastatic Breast CancerJNCI Journal of the National Cancer Institute, 1991
- Direct, highly efficient synthesis from (S)-(+)-phenylglycine of the taxol and taxotere side chainsThe Journal of Organic Chemistry, 1991
- Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R,3S)-3-phenylisoserine, and its analogs via chiral 3-hydroxy-4-aryl-.beta.-lactams through chiral ester enolate-imine cyclocondensationThe Journal of Organic Chemistry, 1991
- Semianalytical treatment of solvation for molecular mechanics and dynamicsJournal of the American Chemical Society, 1990
- On the out‐of‐plane deformation of aromatic rings, and its representation by molecular mechanicsJournal of Computational Chemistry, 1987
- The MMP2 calculational methodJournal of Computational Chemistry, 1987
- An efficient, enantioselective synthesis of the taxol side chainThe Journal of Organic Chemistry, 1986