HUMAN SOMATOTROPIN .55. SYNTHESIS AND GROWTH-PROMOTING ACTIVITY OF PEPTIDE ANALOGS OF CARBOXYL TERMINAL PLASMIN FRAGMENT
- 1 January 1978
- journal article
- research article
- Vol. 11 (5), 315-322
Abstract
Three analogs of the carboxyl terminal plasmin fragment of human somatotropin, [Nle170, Ala165,182,189]-human somatotropin-(145-191), [Nle170, Ala165,182,189]-human somatotropin-(140-191), and [Lys135,136,138, Glu137,139, Nle170, Ala165,182,189]-human somatotropin-(135-191) were synthesized by the solid-phase method. The synthetic peptides were assayed for growth-promoting activity and their potency was comparable to that of [S-carbamideomethylcysteine165,182,189]-human somatotropin-(141-191) which was derived from the native hormone.This publication has 4 references indexed in Scilit:
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