CHEMOTAXIS IN LEUKOCYTES

Abstract

The author describes the capillary tube, micro-injn., slide-coverslip, and tissue culture methods of studying chemotaxis in leukocytes; the behavior and rate of locomotion of leukocytes; the width and time relations of the chemotactic field; the kind of leukocyte showing chemotaxis; the microorganisms (bacteria, viruses, protozoa, yeasts), products (histamine, leukotaxine) of injured tissue, and carbohydrates that excite chemotaxis; substances leading to negative chemotaxis; chemotactic effects of miscellaneous substances including some particles having low solubility in water; conditions interfering with chemotaxis; relation of chemotaxis to emigration and phagocytosis ; hypothetical mechanisms; and advantage of leuko-cytic chemotaxis to the organism.