Positron emission tomography in venous ulceration and liposclerosis: study of regional tissue function.
- 29 January 1983
- Vol. 286 (6362), 333-336
- https://doi.org/10.1136/bmj.286.6362.333
Abstract
Oxygen-15 administered by continuous inhalation and emission computed tomography were used to study regional tissue oxygen utilisation and blood flow in the limbs of 11 patients with venous ulceration and five patients with liposclerosis due to venous insufficiency. The results showed increased blood flow and appreciably reduced fractional oxygen extraction in the diseased tissues. These findings indicated a local, functional shunting of blood through the abnormal microcirculation of the skin and subcutaneous tissues. This may be an important factor in the aetiology of the skin changes seen in patients with calf muscle pump failure.Keywords
This publication has 21 references indexed in Scilit:
- The effect of sustained venous hypertension on the skin capillaries of the canine hind limbBritish Journal of Surgery, 1982
- The relationship between the number of capillaries in the skin of the venous ulcer-bearing area of the lower leg and the fall in foot vein pressure during exerciseBritish Journal of Surgery, 1981
- Transverse Section Imaging of Soft Tissue tumors and Peripheral Vascular DiseaseSeminars in Nuclear Medicine, 1980
- Quantitation in Positron Emission Computed TomographyJournal of Computer Assisted Tomography, 1979
- The continuous inhalation of Oxygen-15 for assessing regional oxygen extraction in the brain of manThe British Journal of Radiology, 1976
- Arteriovenous Shunts in Primary Varicosis? A Critical EssayVascular Surgery, 1972
- The measure in vivo of regional cerebral oxygen utilization by means of oxyhemoglobin labeled with radioactive oxygen-15Journal of Clinical Investigation, 1970
- MICROVASCULAR PATTERN AND BLOOD STASIS IN SKIN DISEASEBritish Journal of Dermatology, 1969
- Pathogenic Study of Varicose VeinsAngiology, 1953
- STUDY OF THE TENDENCY TO EDEMA FORMATION ASSOCIATED WITH INCOMPETENCE OF THE VALVES OF THE COMMUNICATING VEINS OF THE LEG. OXYGEN TENSION OF THE BLOOD CONTAINED IN VARICOSE VEINSJournal of Clinical Investigation, 1938