Deafness and the Laurence-Moon-Biedl Syndrome

Abstract

2 families of this syndrome are reported. In the first family the parents were first cousins. There were 9 children[long dash]2 females showing the complete syndrome, 1 female who died young but is alleged to have had polydactyly, 2 male deaf mutes with no signs of the syndrome, 2 normal females and 2 normal males. A survey of the literature shows that deaf mutism in Laurence-Moon-Biedl cases and their sibs is 30 times as high as in the general population. In the second family the parents were unrelated. There were 2 children- -1 female showing the complete syndrome, and 1 male showing the syndrome except for polydactyly.