The social effect of Huntington's Chorea on reproductive effectiveness
- 1 January 1976
- journal article
- Published by Wiley in Annals of Human Genetics
- Vol. 39 (3), 375-379
- https://doi.org/10.1111/j.1469-1809.1976.tb00142.x
Abstract
An attempt has been made to account for the observed departures from a model of a simple single-locus inheritance in Huntington's Chorea. It is postulated that an indirect effect of the abnormal allele lies in its social effects on individuals in the family group whether they bear the allele or not. This acts by influencing their mate-finding and reproductive behaviour so as to produce the observed statistical anomalies.Keywords
This publication has 8 references indexed in Scilit:
- Relation of parental age to rigidity in Huntington's diseaseJournal of Medical Genetics, 1974
- Recurrence risks from family history and metric traitsAnnals of Human Genetics, 1974
- Evidence of genetic heterogeneity in Huntington's choreaJournal of Neurology, Neurosurgery & Psychiatry, 1972
- The Royal Australasian College Of PhysiciansAustralian and New Zealand Journal of Medicine, 1972
- A statistical study of half-sibships born to parents affected with Huntington's disease.Journal of Medical Genetics, 1972
- HUNTINGTON'S CHOREA: A PARTIAL MODEL OF THE AGEING PROCESSThe Medical Journal of Australia, 1971
- Infection as the Etiology of Spongiform Encephalopathy (Creutzfeldt-Jakob Disease)Science, 1969
- The genetical evolution of social behaviour. IJournal of Theoretical Biology, 1964