An Epidemic, Toxin Gene–Variant Strain ofClostridium difficile
Top Cited Papers
Open Access
- 8 December 2005
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 353 (23), 2433-2441
- https://doi.org/10.1056/nejmoa051590
Abstract
Recent reports suggest that the rate and severity of Clostridium difficile–associated disease in the United States are increasing and that the increase may be associated with the emergence of a new strain of C. difficile with increased virulence, resistance, or both.Keywords
This publication has 32 references indexed in Scilit:
- Comparative analysis of Clostridium difficile clinical isolates belonging to different genetic lineages and time periodsJournal of Medical Microbiology, 2004
- Distribution of Clostridium difficile variant toxinotypes and strains with binary toxin genes among clinical isolates in an American hospitalJournal of Medical Microbiology, 2004
- Clostridium difficile associated diarrhoea in hospitalised patients: onset in the community and hospital and role of flexible sigmoidoscopyGut, 2004
- Molecular Analysis of the Pathogenicity Locus and Polymorphism in the Putative Negative Regulator of Toxin Production (TcdC) among Clostridium difficile Clinical IsolatesJournal of Clinical Microbiology, 2002
- Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficileFEMS Microbiology Letters, 2000
- Epidemics of Diarrhea Caused by a Clindamycin-Resistant Strain ofClostridium difficilein Four HospitalsNew England Journal of Medicine, 1999
- Clostridium Difficile-Associated Diarrhea and ColitisInfection Control & Hospital Epidemiology, 1995
- Colitis Induced by Clostridium difficileClinical Infectious Diseases, 1979
- Partial Purification and Characterization of a Cytotoxin from Clostridium difficileClinical Infectious Diseases, 1979
- Clindamycin-Associated Colitis Due to a Toxin-Producing Species of Clostridium in HamstersThe Journal of Infectious Diseases, 1977