HIF-1: upstream and downstream of cancer metabolism
Top Cited Papers
- 26 November 2009
- journal article
- review article
- Published by Elsevier in Current Opinion in Genetics & Development
- Vol. 20 (1), 51-56
- https://doi.org/10.1016/j.gde.2009.10.009
Abstract
No abstract availableKeywords
This publication has 47 references indexed in Scilit:
- Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeuticsOncogene, 2009
- mTOR and HIF-1α-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndromeProceedings of the National Academy of Sciences, 2009
- Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasisProceedings of the National Academy of Sciences, 2009
- Hypoxia inducible factor-2α: a critical mediator of aggressive tumor phenotypesCurrent Opinion in Genetics & Development, 2009
- HIF‐1α and HIF‐2α have divergent roles in colon cancerInternational Journal of Cancer, 2008
- Pyruvate Dehydrogenase Complex Activity Controls Metabolic and Malignant Phenotype in Cancer CellsJournal of Biological Chemistry, 2008
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase PathwayMolecular Cell, 2008
- Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to HypoxiaJournal of Biological Chemistry, 2008
- HIF-Dependent Antitumorigenic Effect of Antioxidants In VivoCancer Cell, 2007
- Metabolic targeting of hypoxia and HIF1 in solid tumors can enhance cytotoxic chemotherapyProceedings of the National Academy of Sciences, 2007