THE EFFECT OF MECHANICAL EXSUFFLATION ON RESPIRATORY GAS EXCHANGE IN CHRONIC PULMONARY EMPHYSEMA
Open Access
- 1 November 1953
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 32 (11), 1192-1196
- https://doi.org/10.1172/jci102845
Abstract
The effect of the mechanical exsufflator on respiratory gas exchange in emphysema compared to the effect of the conventional respirator is presented. In 4 cases 30 min. of exsufflator therapy resulted in an increased min. ventilation and beneficial effect on arterial pH, CO2 tension, and O2 saturation. Respirator therapy for 60 min. resulted in no appreciable change. Uncompensated respiratory acidosis was produced in 8 patients with emphysema by the administration of O2. The acid-base disturbance was effectively treated by a short period of exsufflation. In 3 out of 5 cases the low level of CO2 was maintained after 2 hrs. while the O2 saturation fell below the control level. The beneficial effect of the combined use of the exsufflator and the respirator in the treatment of a patient with emphysema who developed respiratory acidosis is demonstrated. It is suggested that the use of exsufflation is a valuable adjunct to therapy in respiratory acidosis.This publication has 9 references indexed in Scilit:
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