Intestinal Permeability Enhancement: Efficacy, Acute Local Toxicity, and Reversibility
- 1 January 1994
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 11 (8), 1132-1142
- https://doi.org/10.1023/a:1018984731584
Abstract
The absorption of the polar drug phenol red was assessed in a rat intestinal perfusion model, in the presence of a variety of potential intestinal permeability enhancers. Both the absorption rate...Keywords
This publication has 27 references indexed in Scilit:
- Intestinal drug absorption enhancement: An overviewPharmacology & Therapeutics, 1989
- Villus contraction aids repair of intestinal epithelium after injuryAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 1989
- Morphology of Rat Gastric Mucosal Damage, Defense, and Restitution in the Presence of Luminal EthanolGastroenterology, 1985
- The influence of bile salt structure on self-association in aqueous solutions.Journal of Biological Chemistry, 1983
- Effect of pharmaceutical adjuvants on the rectal permeability of drugs. III. Effect of repeated administration and recovery of the permeability.CHEMICAL & PHARMACEUTICAL BULLETIN, 1983
- EFFECT OF MOLECULAR-STRUCTURE ON BILE ACID-INDUCED ALTERATIONS IN ABSORPTIVE FUNCTION, PERMEABILITY, AND MORPHOLOGY IN THE PERFUSED RABBIT COLON1979
- Effects of Anionic Surfactants on Hamster Small Intestinal Membrane Structure and Function: Relationship to Surface ActivityGastroenterology, 1977
- Perfusion of the Hamster Jejunum with Conjugated and Unconjugated Bile Acids: Inhibition of Water Absorption and Effects on MorphologyGastroenterology, 1972
- Colonic Secretion of Water and Electrolytes Induced by Bile Acids: Perfusion Studies in ManJournal of Clinical Investigation, 1971
- STUDIES ON LIPID METABOLISM IN THE SMALL INTESTINE WITH OBSERVATIONS ON THE ROLE OF BILE SALTS*†Journal of Clinical Investigation, 1960