Serotonin: Radioimmunoassay
- 30 March 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 179 (4080), 1340-1341
- https://doi.org/10.1126/science.179.4080.1340
Abstract
The development of a radioimmunoassay for serotonin is described. Serotonin is made antigenic by coupling it to bovine serum albumin. Thrombocyte-free plasma instead of serum from the immunized animals is used for radioimmunoassay. Less than 1 ng serotonin can be measured by this procedure.Keywords
This publication has 7 references indexed in Scilit:
- A method for the determination of serotonin and norepinephrine in discrete areas of rat brainInternational Journal of Neuropharmacology, 1968
- ANTIBODIES TO SEROTONINCanadian Journal of Biochemistry, 1967
- ACID MONOAMINE METABOLITES OF CEREBROSPINAL FLUID IN MENTAL DEPRESSION AND MANIAJournal of Neurochemistry, 1966
- A sensitive and specific fluorescence assay for tissue serotoninBiochemical Pharmacology, 1965
- Enzymatic O-Methylation of N-Acetylserotonin to MelatoninScience, 1960
- THE RELATIVE ACTIVITIES OF SOME TRYPTAMINE ANALOGUES ON THE ISOLATED RAT STOMACH STRIP PREPARATIONBritish Journal of Pharmacology and Chemotherapy, 1959
- The histamine and serotonin content of the platelets and polymorphonuclear leucocytes of various speciesThe Journal of Physiology, 1954