Stimulation of granulocytopoiesis by a diffusible factor in vivo
Open Access
- 1 September 1971
- journal article
- Published by American Society for Clinical Investigation in JCI Insight
- Vol. 50 (9), 2004-2007
- https://doi.org/10.1172/jci106693
Abstract
A millipore diffusion chamber system was used to cultivate mouse marrow in the abdomens of irradiated and unirradiated host mice for 24 hr. When the irradiated hosts were 72, 96, or 120 hr postirradiation, the number of blasts and promyelocytes in the implanted chambers after cultivation was greater than those in the same marrow cultivated in unirradiated hosts. These data indicate that in vivo, there is stimulation of granulocytopoiesis by a diffusible factor or factors.Keywords
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