MECHANISM OF GRAFT-VERSUS-HOST-INDUCED LYMPHADENOPATHY IN MICE
Open Access
- 1 May 1973
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 137 (5), 1293-1302
- https://doi.org/10.1084/jem.137.5.1293
Abstract
Graft-vs.-host (GVH)-induced lymphadenopathy of the popliteal lymph node has been produced in C57BL/6 x A/J F1 (BAF1) mice by injecting A/J spleen cells into the rear footpads. By giving 51Cr-labeled BAF1 lymphoid cells intravenously to the hosts, 24 h before sacrifice, we have demonstrated that a large portion of the GVH-induced lymphadenopathy is due to the trapping of circuating lymphocytes in the challenged lymph nodes.Keywords
This publication has 34 references indexed in Scilit:
- THE ALLOGENEIC EFFECT IN INBRED MICEThe Journal of Experimental Medicine, 1972
- THE IMMUNOLOGICALLY SPECIFIC RETENTION OF RECIRCULATING LONG-LIVED LYMPHOCYTES IN LYMPH NODES STIMULATED BY XENOGENEIC ERYTHROCYTESThe Journal of Experimental Medicine, 1972
- DETECTION OF ALLOANTIGENS ON HUMAN AND CHIMPANZEE SKIN FIBROBLASTS BY IN VITRO CYTOTOXICITY AND COLONY INHIBITION TESTSTransplantation, 1971
- A LYMPH NODE WEIGHT ASSAY FOR THE GRAFTVERSUS- HOST ACTIVITY OF RAT LYMPHOID CELLSTransplantation, 1970
- LOCAL AND REGIONAL FORMS OF GRAFT-VERSUS-HOST DISEASE IN LYMPH NODESTransplantation, 1968
- Quantitative studies on tissue transplantation immunity. VII. The normal lymphocyte transfer reactionProceedings of the Royal Society of London. B. Biological Sciences, 1966
- THE ORIGIN OF THE CELLS IN THE EFFERENT LYMPH FROM A SINGLE LYMPH NODEThe Journal of Experimental Medicine, 1965
- INVASION AND DESTRUCTION OF HOMOLOGOUS KIDNEY BY LOCALLY INOCULATED LYMPHOID CELLSThe Journal of Experimental Medicine, 1964
- THE USE OF RETICULOENDOTHELIAL FUNCTION FOR STUDYING GRAFT-VERSUS-HOST REACTION IN THE PRESENCE OF POTENTIAL HOST-VERSUS-GRAFT REACTION.1964
- SPLENOMEGALY AS A HOST RESPONSE IN GRAFT-VERSUS-HOST DISEASE1961