Morphological Study of Autologous Rosettes (A‐RFC)
- 1 January 1979
- journal article
- research article
- Published by Wiley in Scandinavian Journal of Immunology
- Vol. 9 (1), 15-21
- https://doi.org/10.1111/j.1365-3083.1979.tb02701.x
Abstract
The morphology of A-RFC was studied by light and EM. A-RFC were obtained from the spleen of adult thymectomized (ATx) or nude mice, and from neonatal thymus grafts during the regeneration phase. Among the auto-rosettes seen by light microscopy, 76% of them were formed by lymphoid cells which included a high proportion of large lymphocytes (48%). EM study performed after isolation of A-RFC by micromanipulation demonstrated that 74% were formed by large lymphoid cells with an immature nucleus. The finding of such large-sized lymphoid cells with immature nuclei indicates that A-RFC might belong to an immature T [thymus-derived] cell class.This publication has 19 references indexed in Scilit:
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