Angiogenesis Induced by "Normal" Human Breast Tissue: A Probable Marker for Precancer
- 15 October 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 218 (4569), 293-295
- https://doi.org/10.1126/science.6181563
Abstract
Normal human breast lobules, freshly isolated by precision microdissection of tissue stained with methylene blue chloride, were assayed for their ability to induce neovascularization (angiogenesis) in rabbit irises. Histologically, normal lobules from cancerous breast induced angiogenesis twice as often as lobules from noncancerous breasts, suggesting that preneoplastic transformation is diffuse.This publication has 18 references indexed in Scilit:
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