Brain proteins in experimental portal-systemic shunting
- 29 January 2009
- journal article
- research article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 59 (5), 275-280
- https://doi.org/10.1111/j.1600-0404.1979.tb02938.x
Abstract
Experimental portal-systemic shuntings is accompanied by a reduction of the soluble brain proteins. Isoelectric focusing does not indicate any selective decrease of 1 particular protein or group of proteins. The reduction persists with sustained shunting. The interference with brain protein metabolism is compatible with a grossly normal behavior, alertness and locomotion. [Portal-systemic shunting is thought to be an important prerequisite for hepatic encephalopathy.].Keywords
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