On the Formation of Acetylcholine in the Nerve Axon
- 7 September 1945
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 102 (2645), 250-251
- https://doi.org/10.1126/science.102.2645.250
Abstract
Choline acetylase, the precursor of acetylcholine, was found in the axon in rabbit sciatic nerves. About 50 [mu]g/g/hr. was formed as compared with 100-150 [mu]g in guinea pig brain. Following section of the nerve the enzyme activity decreased. The presence of these enzyme systems offers evidence for the formation of acetylcholine in the axon and its importance in the nerve impulse.This publication has 9 references indexed in Scilit:
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