Immunity to Plasmodium chabaudi adami in the B-cell-deficient mouse

Abstract

P. c. adami (556KA) infection in B cell-deficient mice results in an activation of a T cell-dependent immune mechanism which terminates acute malaria in a similar way to that seen in immunologically intact mice. These immunized B cell-deficient mice were resistant to homologous challenge infection as well as infections initiated with P. vinckei but not with P. yoelii and P. berghei.