Regions containing repeating base-pairs in DNA from some oncogenic and nononcogenic animal viruses.
- 1 June 1967
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 57 (6), 1720-1725
- https://doi.org/10.1073/pnas.57.6.1720
Abstract
On the basis of DNA ribopolymer reactivities, differences in content of dC [deoxycytosine]-and dA [deoxyadenosine]-rich sequences were observed among DNA''s from nononcogenic, weakly oncogenic, and highly oncogenic adeno-viruses. SV40 [Simian vacuolating] virus DNA was also analyzed. The oncogenic adenovirus DNA''s contain fewer dC-rich sequences and more dA-rich sequences than DNA''s from the nononcogenic adeno-viruses. SV40 virus DNA contains relatively more dA-rich sequences than the highly oncogenic adenovirus DNA''s. There are few, if any, dC-rich sequences detectable in SV40 virus DNA. These findings may relate to viral oncogenicity.This publication has 18 references indexed in Scilit:
- [Homology between the genome of avian myeloblastosis virus (AMV) and the cellular genome].1966
- Nucleic acid homology studies of SV 40 virus-transformed and normal hamster cells.Proceedings of the National Academy of Sciences, 1966
- The mechanism of viral carcinogenesis by DNA mammalian viruses: viral-specific RNA in polyribosomes of adenovirus tumor and transformed cells.Proceedings of the National Academy of Sciences, 1966
- Biochemical studies on adenovirus multiplication. IX. Chemical and base composition analysis of 28 human adenoviruses.Proceedings of the National Academy of Sciences, 1965
- Polyoma Virus Genetic Material in a Virus-Free Polyoma-Induce TumorScience, 1964
- The purification of simian virus 40Virology, 1964
- Biochemical studies on adenovirus multiplicationVirology, 1963
- ONCOGENIC EFFECTS IN HAMSTERS OF HUMAN ADENOVIRUS TYPES 12 AND 18Proceedings of the National Academy of Sciences, 1962
- The Quest for Human Cancer VirusesScience, 1962
- Identification of the oncogenic substance in rhesus monkey kidney cell cultures as simian virus 40Virology, 1962