Abstract
Microsomal sialyl transferase and galactosyl transferase activities of herpes simplex virus-infected GMK [green monkey kidney] and BHK [baby hamster kidney] cells were studied. Apparent Km values calculated for sialyl and galactosyl transferases differed significantly from the corresponding values of uninfected cells. Both transferases of HSV-infected cells demonstrated acceptor specificities different from those of uninfected cells. Herpes simplex virus might influence glycosylation of proteins by modifying the glycosyl transferases of the infected cells.