Relationship between Herpesvirus ateles-associated Nuclear Antigen (HATNA) and the Number of Virus Genome Equivalents in HVA-carrying Lymphoid Lines
- 1 February 1981
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 52 (2), 221-226
- https://doi.org/10.1099/0022-1317-52-2-221
Abstract
Summary A DNA-binding antigen (HATNA) was demonstrated in 7 out of 14 cell lines carrying Herpesvirus ateles (HVA) by the acid-fixed nuclear-binding technique. The seven HATNA-positive lines had means of 95, 96, 103, 177, 240, 343 and 326 virus genome equivalents/cell. For the seven HATNA-negative lines, the figures were 4, 8, 10, 33, 39, 72 and 110. This indicates a relationship between the number of HVA genome equivalents/cell and the detectability of HATNA. This association was independent of the virus producer status of the lines.This publication has 5 references indexed in Scilit:
- Relationship between Epstein-Barr Virus Genome Number, Amount of Nuclear Antigen, and Early Antigen Inducibility in Diploid and Tetraploid Lymphoma Cells of Related OriginIntervirology, 1979
- Biological activity of purified simian virus 40 T antigen proteins.Proceedings of the National Academy of Sciences, 1978
- Herpesvirus ateles DNA and Its Homology with Herpesvirus saimiri Nucleic AcidJournal of Virology, 1978
- Solubilization of the Epstein-Barr virus-determined nuclear antigen and its characterization as a DNA-binding proteinJournal of Virology, 1977
- Morphological and Virological Investigations on Cultured Burkitt Tumor Lymphoblasts (Strain Raji)2JNCI Journal of the National Cancer Institute, 1966