Studies on the Pathogenesis of the Generalized Shwartzman Reaction
- 1 January 1964
- journal article
- research article
- Published by Georg Thieme Verlag KG in Thrombosis and Haemostasis
- Vol. 12 (02), 452-461
- https://doi.org/10.1055/s-0038-1655558
Abstract
The generalized Shwartzman reaction (gSr) was produced in pregnant rabbits by means of a single intravenous injection of E.-coli endotoxin. The animals developed a profound and a haemorrhagic diathesis. The haemorrhagic condition is thought to be the result of an acute consumption of the plasma-factors of the coagulation system. The pathogenesis of the gSr is discussed in the light of literature dealing with this phenomenon. * Present address: Dept. of Haematology. Tufts-New England Medical Center, Boston, 11, Mass. 02111, USA.This publication has 11 references indexed in Scilit:
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