B12 Metabolism and Multiple Sclerosis.

Abstract
The serum vitamin B12 and glutathione levels in red cells were determined in patients with multiple sclerosis (M.S.). Both substances were found to be reduced in M.S. patients as compared to normal subjects. Following intramuscular injection of vitamin B12, M.S. subjects showed reduced ability to retain the vitamin. They did absorb it adequately when taken orally. A vitamin B12-tannate derivative was found to be excreted more slowly by M.S. patients than aqueous vitamin B12.