Bioactivity of titanium treated with hydrogen peroxide solutions containing metal chlorides

Abstract

Commercially available pure metallic titanium was chemically treated at 60°C for 24 h with H₂O₂ solutions containing various metal chlorides to provide titanium with bioactivity, that is, to give it the ability to form a biologically active bone-like apatite layer on the surface. After the chemical treatment the titanium specimens were soaked in a simulated body fluid (the Kokubo solution). Apatite was found to deposit on the specimens treated with the H₂O₂/TaCl₅ and H₂O₂/SnCl₂ solutions. X-ray photoelectron spectroscopic (XPS) study of the specimens treated with those H₂O₂ solutions indicated that basic Ti-OH groups in titania hydrogel layers on their surfaces were responsible for apatite nucleation and growth. © 1997 John Wiley & Sons, Inc.